Oxford Street, Piccadilly Circus and Regent's Park are nearby the Melia White House. Piccadilly Circus is known for its nightlife and Oxford Street for its many high-end shopping establishments. Public transit is easily-accessible to more distant locations via three separate tube stations, all within walking distance of this hotel in London. The London Heathrow Airport is accessible from the Melia White House via the tube system and constitutes a roughly 45-minute journey. The hotel offers 24-hour desk service for travelers.

Guestrooms at the Melia White House are provided with air conditioning, radios, hairdryers, in-room safes and direct-dial telephones. Trouser presses are also made available. Internet access is provided in the rooms and throughout the hotel. There is parking available at an offsite lot and there are non-smoking options for rooms.

The Melia White House is provided with a contemporary feel and offers luxury-level accommodations near Regent's Park. It has two restaurants onsite, one Mediterranean, one international. It also has a full service bar and 24-hour room service. It is central to most of London's most-visited sites.